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  • NICE - Endorsed Technology Appraisals 2025/2026

    Topics:
    • Safety and quality

    It is important to note that the advice contained within the guidance does not override or replace the individual responsibility of health professionals to make appropriate decisions in the circumstances of their individual patients, in consultation with the patient and/or guardian or carer. This would, for example, include situations where individual patients have other conditions or complications that need to be taken into account in determining whether the NICE guidance is fully appropriate in their case.

    Technology Appraisals Endorsement Process

    The Department has reviewed its process for the endorsement, implementation, monitoring and assurance of NICE Technology Appraisals in Northern Ireland. The new arrangements are detailed in following circulars, which is effective from 18th December 2013;

    NICE Technology Appraisals – Process for Endorsement, Implementation, Monitoring and Assurance in Northern Ireland – HSC (SQSD) 02/13.

    For information, details of the previous arrangement can be found on the following circular;

    NICE Technology Appraisals and Clinical Guidelines – New Process for Endorsement, Implementation, Monitoring and Assurance in Northern Ireland – HSC (SQSD) 04/11

    2025/2026

    The following technology appraisals have been endorsed during 2025/26. Information on technology appraisals endorsed in previous years can be found on the homepage.

    May 2025

    TA1057 - Relugolix–estradiol–norethisterone for treating symptoms of endometriosis | Guidance | NICE

    TA1056 - Molnupiravir for treating COVID-19

    TA1055 - Rucaparib for maintenance treatment of advanced ovarian, fallopian tube and peritoneal cancer after response to first-line platinum-based chemotherapy

    TA1054 - Ruxolitinib for treating acute graft versus host disease that responds inadequately to corticosteroids in people 12 years and over

    TA1053 - Cladribine for treating active relapsing forms of multiple sclerosis

    April 2025

    TA1051 - Efanesoctocog alfa for treating and preventing bleeding episodes in haemophilia A in people 2 years and over

    TA1050 - Fenfluramine for treating seizures associated with Lennox–Gastaut syndrome in people 2 years and over

    TA1049 - Overview | Blinatumomab with chemotherapy for consolidation treatment of Philadelphia-chromosome-negative CD19-positive minimal residual disease-negative B-cell precursor acute lymphoblastic leukaemia | Guidance | NICE

    TA1048 - Lisocabtagene maraleucel for treating relapsed or refractory large B-cell lymphoma after first-line chemoimmunotherapy when a stem cell transplant is suitable

    TA1046 - Zolbetuximab with chemotherapy for untreated claudin-18.2-positive HER2-negative unresectable advanced gastric or gastro-oesophageal junction adenocarcinoma

     

     

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