NICE - Antimicrobial Prescribing Guidelines

NICE Antimicrobial Guidelines are evidence-based guidelines for managing common infections in the context of tackling antimicrobial resistance – specifically in relation to bacterial infection and antibiotic use.

The Northern Ireland Management of Infection Guidelines for Primary and Community Care reflect these guidelines. They are available on the ‘Microguide App’ for mobile devices or via the Northern Ireland Formulary website.

These guidelines will also support the work of HSC Trusts in their antibiotic stewardship.


It is important to note that the advice contained within the guidance does not override or replace the individual responsibility of health professionals to make appropriate decisions in the circumstances of their individual patients, in consultation with the patient and/or guardian or carer. This would, for example, include situations where individual patients have other conditions or complications that need to be taken into account in determining whether the NICE guidance is fully appropriate in their case.

The following Antimicrobial Guidelines have been endorsed by DoH: 

June 2018

NG79 - Sinusitis (Acute): Antimicrobial prescribing

NG81 - Sore Throat (Acute): Antimicrobial prescribing

NG91 - Otitis Media (Acute): Antimicrobial prescribing

November 2018

NG109 - Urinary Tract Infection (Lower): Antimicrobial prescribing

NG110 - Prostatitis (Acute): Antimicrobial prescribing

NG111 - Pyelonephritis (Acute): Antimicrobial prescribing

NG112 - Urinary Tract Infection (Recurrent): Antimicrobial prescribing

NG113 - Urinary Tract Infection (Catheter-Associated): Antimicrobial prescribing

January 2019

NG117 - Bronchiectasis (Non-Cystic Fibrosis), Acute Exacerbation: Antimicrobial prescribing

NG114 - Chronic Obstructive Pulmonary Disease (Acute Exacerbation): Antimicrobial prescribing

February 2019

NG120 - Cough (Acute): Antimicrobial prescribing

September 2019

NG138 - Pneumonia (Community-Acquired): Antimicrobial Prescribing

NG139 - Pneumonia (Hospital-Acquired): Antimicrobial Prescribing

NG141 - Cellulitis and Erysipelas: Antimicrobial Prescribing

February 2020

NG152 - Leg Ulcer Infection: Antimicrobial Prescribing

NG153 - Impetigo: antimicrobial prescribing - 26 February 2020

September 2020

NG182 - Insect bites and stings: antimicrobial prescribing - 23 September 2020

November 2020

NG184 - Human and animal bites: antimicrobial prescribing

March 2021

NG190 - Secondary bacterial infection of eczema and other common skin conditions: antimicrobial prescribing Note this guideline updates and replaces some recommendations on managing infections in NICE Clinical Guideline CG57, which was endorsed by the DoH in July 2008.

July 2021

NG199 - Clostridioides difficile infection: antimicrobial prescribing - 29 July 2021

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